Clinical implications of home-based sperm testing

In the study by Samplaski et al. (1Samplaski M.K. Falk O. Honig S. Shin D. Matthews W. Smith J.F. Development and validation of a novel mail-in semen analysis system correlation between one hour delayed testing.Fertil Steril. 2021; 115: 922-929Scopus (2) Google Scholar), authors develop validate home-collected, kit that can be analyzed up to 52 hours after collection. The challenges tests are time elapsed since collection conditions which samples exposed during transportation, both may impact result. Using provided from 164 healthy men, created an algorithm model predict changes in over time. They concluded this meets or exceeds laboratory standards. correctly note barriers in-office analysis, including physical access laboratories, difficulty providing fresh sample through masturbation, current COVID-19 pandemic, has mandated less physician-patient contact Scholar). Current at-home test kits best suited for screening identifying men who should seek professional workup. also require considerable processing patient, lead inaccurate results. presented manuscript appears have better reliability room error importantly Clinical Laboratory Improvement Amendments standards (2Carrell D.T. Cartmill A brief review proposed federal government regulation assisted reproduction laboratories United States.J Androl. 2006; 23: 611-617Google ability perform testing numerous clinical patient implications, reducing anxiety, improving convenience, potentially see higher levels compliance (3Bradshaw A. Ballon-Landa E. Owusu R. Hsieh T.C. Poor with postvasectomy testing: factors barriers.Urology. 2020; 136: 146-151Abstract Full Text PDF PubMed Scopus (6) Several areas sperm valuable include initial workup infertility as potential tool identify whether individual requires standard if additional investigations required, testing, routine is required vasovasostomy, vasoepididymostomy, varicocelectomy. Further, another clinically important implication standardization Routine fraught interobserver variability. As such, centralized location evaluation minimize variability and, thus, improve diagnostic utility results (4Filimberti Degl’Innocenti Borsotti M. Quercioli Piomboni P. Natali I. al.High andrology Tuscany (Italy): experience external quality control (EQC) programme.Andrology. 2013; 1: 401-407Crossref (32) we continue improvements technology, patients their immediately via smartphones (5Agarwal Selvam M.K.P. Sharma Master K. Gupta al.Home device versus analyzer: comparison motile concentration.Fertil 2018; 110: 1277-1284Abstract (23) This exciting field new technologies develop, must ensure accuracy laboratory-based testing. testingFertility SterilityVol. 115Issue 4PreviewTo novel, (SA) system. Full-Text